Prince Henry’s Institute

 

Katie Meehan

 

Appointments

• Witchery/Madison Research Fellow

• Sessional Lecturer, School of Life and Physical Sciences, RMIT University

 

Profile

Dr Meehan’s PhD was undertaken at the University of Western Australia and she then undertook a post-doctoral studies on prostate cancer at the British Columbian Cancer Agency in Canada.

She was appointed as a Research Associate at the University of Arizona  where she then gained experience in the field of immunology and allergies.

Katie joined PHI in 2008.

In 2009 Kate was made a Witchery/Madison Research Fellow as a result of funding provided by the Ovarian Cancer Research Foundation.

 

Current Research

Dr Meehan is currently focused on applying a range of proteomic technologies to define a set of blood proteins for the early prediction of ovarian hyperstimulation syndrome. It is anticipated that a natural flow on from this research will contribute to understanding the pathophysiology of this syndrome. Functional studies will be the next phase of this research program.

These ongoing studies involve close collaboration with Monash IVF. Dr Meehan is also interested in applying the latest proteomic and bioinformatics advances to her research. In particular, she is interested in applying iTRAQ and label free mass spectrometry approaches to her research.  

 

Expertise

Translational research, infertility, ovarian cancer. 

 

Current Research

• Circulating markers of ovarian cancer

• Auto-immune response in cancer patients

• Nanoparticle technology for the identification of novel cancer markers

• Fallopian tube as the origin of epithelial ovarian cancers

 

Recent Achievements

• Canadian Proteomics Initiative Poster Prize Keystone conference scholarship (DOE grant award)

• Australian Society of Biochemistry and Molecular Biology Student Poster Prize

• John Leslie and Dorise Barron Scholarship, The Grand Lodge of Western Australian Freemasons

• Richard Walter Gibbon Medical Research Scholarship, National Award

• Bev Wishaw Scholarship, Urological Research Centre and Department of Surgery Scholarship, University of Western Australia  

 

Service to the Scientific Community

• Member, Australian Proteomics Society 

 

Selected Publications

Cohen RJ, McNeal JE, Redmond SL, Meehan K, Thomas R, Wilce M, Dawkins HJ. Luminal contents of benign and malignant prostatic glands: correspondence to altered secretory mechanisms. Human Pathology 2000;31(1):94-100.

Meehan K, Holland J, Dawkins HJ. Identification of differentially expressed proteins in the proteome of normal prostate compared with malignant prostate. The Prostate 2002; 50(1):54-63.

Meehan K and Sadar, M. Androgens and androgen receptor in prostate and ovarian malignancies. Frontiers in Bioscience 2003; 8:780-800.

Sadar M and Meehan K. Quantitative profiling of LNCaP prostate cancer cells using isotope-coded affinity tags and mass spectrometry. Provisional patent application.

Holland JW, Meehan KL, Redmond SL, Dawkins HJ. Purification of the Keratan Sulfate proteoglycan expressed in prostatic secretory cells and its identification as lumican. The Prostate 2004; 59(3):252-9.

Meehan K, and Sadar, M. Quantitative profiling of LNCaP prostate cancer cells using isotope-coded affinity tags and mass spectrometry. Proteomics 2004; 4(4):1116-34.